Flow-injection Spectrophotometric Determination of N-acetyl-L-cysteine Based on Coupled Redox-complexation Reaction
نویسندگان
چکیده
منابع مشابه
Kinetic spectrophotometric determination of N-acetyl-L-cysteine based on a coupled redox-complexation reaction.
A novel simple kinetic spectrophotometric method for the determination of N-acetyl-L-cysteine (NAC) has been developed and validated. The proposed method is based on a coupled redox-complexation reaction, the first step of which is the reduction of Fe(3+) by NAC; the second one includes the complexation of Fe(2+), resulting from the preceding redox reaction, with 2,4,6-trypyridyl-s-triazine (TP...
متن کاملFlow injection spectrophotometric determination of N-acetyl-L-cysteine as a complex with palladium(II).
We describe a new method using flow-injection analysis with spectro-photometric detection, suitable for the determination of N-acetyl-L-cysteine (NAC). The proposed method is appropriate for the determination of NAC in reaction with Pd(2+) ions in the concentration range from 1.0 × 10(-5) mol L(-1) to 6.0 × 10(-5) mol L(-1). The detection limit NAC was 5.84 × 10(-6) mol L(-1) and the recorded r...
متن کاملSpectrophotometric Determination of N-Acetyl-L-Cysteine and N-(2-Mercaptopropionyl)-Glycine in Pharmaceutical Preparations
A simple spectrophotometric method for the determination of N-acetyl-L-cysteine (NAC) and N-(2-mercaptopropionyl)glycine (MPG) in pharmaceutical preparations was developed, validated, and used. The proposed equilibrium method is based on a coupled two-step redox and complexation reaction. In the first step, Fe(III) is reduced to Fe(II) by NAC or MPG. Subsequently, Fe(II) is complexed with 2,4,6...
متن کاملKinetic Spectrophotometric Determination of N-acetyl-L-cysteine Based on the Reduction of Copper(II)-neocuproine Reagent
A novel simple kinetic spectrophotometric method for the determination of N-acetyl-L-cysteine (NAC) has been developed and validated. The proposed method is based on the reduction of Cuneocuproine reagent to Cu-neocuproine with the analyte, in a Britton-Robinson buffer solution (pH = 3.0). The non-steady state absorbance of the formed Cu-neocuproine complex is measured at 458 nm. The initial ra...
متن کاملA simple flow injection spectrophotometric determination of nitrite based on its reaction with thiourea.
A simple flow injection spectrophotometric method for the determination of nitrite is described. Nitrite injected into the flow system reacts with thiourea in acidic medium and the generated thiocyanate ion reacts with Fe(III) in the reagent solution to produce a highly colored product. The influences of chemical and physical parameters including reagent concentrations, sample volume injected, ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Croatica Chemica Acta
سال: 2011
ISSN: 0011-1643,1334-417X
DOI: 10.5562/cca1753